Discovery of chiral N,N-disubstituted trifluoro-3-amino-2-propanols as potent inhibitors of cholesteryl ester transfer protein

J Med Chem. 2000 Nov 30;43(24):4575-8. doi: 10.1021/jm000337b.
No abstract available

MeSH terms

  • Carrier Proteins / antagonists & inhibitors
  • Carrier Proteins / blood
  • Carrier Proteins / chemistry*
  • Cholesterol Ester Transfer Proteins
  • Cholesterol Esters / blood*
  • Crystallography, X-Ray
  • Glycoproteins*
  • Humans
  • In Vitro Techniques
  • Propanolamines / blood
  • Propanolamines / chemical synthesis*
  • Propanolamines / chemistry
  • Stereoisomerism

Substances

  • CETP protein, human
  • Carrier Proteins
  • Cholesterol Ester Transfer Proteins
  • Cholesterol Esters
  • Glycoproteins
  • Propanolamines
  • SC 795